• can enterocins affect phagocytosis and glutathione-peroxidase in rabbits?

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    جزئیات بیشتر مقاله
    • تاریخ ارائه: 1392/07/24
    • تاریخ انتشار در تی پی بین: 1392/07/24
    • تعداد بازدید: 725
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     the gastrointestinal microbiota in rabbits play an important role in protection against potential pathogens via the development of the mucosal immune system. the gut health, including the microbial and immunological stability, is often influenced by exogenous factors, mainly around the weaning period. therefore, alternative strategies are required to improve the animal’s health. in this study, the diet of rabbits was supplemented with the semi-purified enterocins ent 2019, ent m andent 4231, produced by bacteriocinogenic strains with probiotic properties, rabbit-derivedenterococcus faecium ccm7420 and non rabbit-derived e. faecium strains al41 and ccm4231. the phagocytic activity, index of phagocytic activity and the gluthatione-peroxidase enzyme activity in blood were determined during the ents consumption and also 3 weeks after their cessation. at 21 days into the experiment the highest phagocytic activity was observed in rabbits receiving ent m. a significant increase in phagocytosis was noted in rabbits with ent 2019 over the entire experiment. moreover, a lower gluthatione-peroxidase activity was measured in rabbits receiving ent m and ent2019. no effect of ent 4231 application on the tested parameters was recorded. the ent m and ent2019 improved the digestive immunity and the host’s defense capacities by stimulating leucocyte phagocytosis, without oxidative stress induction in rabbits.

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