• effects of phosphatidyl serine on immune response in the shrimp litopenaeus vannamei

    نویسندگان :
    جزئیات بیشتر مقاله
    • تاریخ ارائه: 1392/07/24
    • تاریخ انتشار در تی پی بین: 1392/07/24
    • تعداد بازدید: 859
    • تعداد پرسش و پاسخ ها: 0
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     phosphatidyl serine plays an important role in animal innate immunity. given its important functions, numerous investigations have been carried out on its immunological function in many animals. however, studies of phosphatidyl serine in the white shrimp litopenaeus vannamei, an economically important animal, are rare. in this paper, we demonstrated influences of injecting phosphatidyl serine (ps) on immune response including some parameters from pro-phenol oxidase activating system (pro-po system) and hemocyanin-derived phenol oxidase activity (hd-po) along with antibacterial and bacteriolytic activities in the white shrimp litopenaeus vannamei with different ps concentrations (5, 10 and 20 μg ml−1). the results showed that ps could affect immune response ofl. vannamei significantly (p<0.05), including total hemocyte counts (thc), po activity from hemocyte, phenol oxidase (po) activity from plasma, hemocyanin concentration, hd-po activity as well as antibacterial and bacteriolytic activities in the plasma. among the lines, 20 μg ml−1 ps had the strongest effect on the above parameters, whereas 5 μg ml−1 had the least effect. the experimental results indicated that ps was able to activate exocytosis of pro-po and formation of hd-po in white shrimp after injection, further regulating the immune process reflected by variation of antibacterial and bacteriolytic activities in a certain way.

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