محبوبترین نویسندگان :
نویسندگان مقالات پربازدید :
مجله زیست شناسی اروپای مرکزی 2014
جزئیات رویداد
همایش ، رویداد ، ژورنال
اینستاگرام تی پی بین

  • galleria mellonella infected with bacillus thuringiensis involves hsp90

    نویسندگان :
    کلمات کلیدی :
    جزئیات بیشتر مقاله
    • تاریخ ارائه: 1392/07/24
    • تاریخ انتشار در تی پی بین: 1392/07/24
    • تعداد بازدید: 944
    • تعداد پرسش و پاسخ ها: 0
    • شماره تماس دبیرخانه رویداد: -
     insects are good models for studying the innate immune response. we report that galleria mellonella larvae infected with entomopathogenic bacteria bacillus thuringiensis kurstaki show changes in the level of hsp90. our experimental approach was to pre-treat larvae with the hsp90-binding compound, 17-dmag, before infection with b. thuringiensis. we show that pre-treated animals display a higher level of immune response. this was mainly manifested by enhanced action of their hemolymph directed toward living bacteria as well as lysozyme activity digesting bacterial peptidoglycan. the observed phenomenon was due to the higher activity of antimicrobial peptideswhich, in contrast to healthy animals, was detected in the hemolymph of the immunestimulated larvae. finally, the physiological significance of our observation was highlighted by the fact that g. mellonella pre-treated with 17-dmag showed a prolonged survival rate after infection with b. thuringiensis than the control animals. our report points to a role for hsp90 in the immune response of g. mellonella after infection with b. thuringiensis at the optimal growth temperature.

سوال خود را در مورد این مقاله مطرح نمایید :

با انتخاب دکمه ثبت پرسش، موافقت خود را با قوانین انتشار محتوا در وبسایت تی پی بین اعلام می کنم
مقالات جدیدترین رویدادها
مقالات جدیدترین ژورنال ها