محبوبترین نویسندگان :
نویسندگان مقالات پربازدید :
آکتا بیومتریال
جزئیات رویداد
اینستاگرام تی پی بین
همایش ، رویداد ، ژورنال
حوزه های تحت پوشش رویداد

  • in vitro corrosion behavior and in vivo biodegradation of biomedical β-ca3(po4)2/mg–zn composites

    نویسندگان :
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    جزئیات بیشتر مقاله
    • تاریخ ارائه: 1392/01/01
    • تاریخ انتشار در تی پی بین: 1392/01/01
    • تعداد بازدید: 574
    • تعداد پرسش و پاسخ ها: 0
    • شماره تماس دبیرخانه رویداد: -
     in this study 5, 10 and 15% β-ca3(po4)2/mg–zn composites were prepared through powder metallurgy methods, and their corrosion behavior and mechanical properties were studied in simulated body fluid (sbf) at 37 °c. the 10% β-ca3(po4)2/mg–zn composite was selected for cytocompatibility assessment and in vivo biodegradation testing. the results identified the α-mg, mgzn and β-ca3(po4)2 phases in these sintered composites. the density and elastic modulus of the β-ca3(po4)2/mg–6% zn composite match those of natural bone, and the strength is approximately double that of natural bone. the 10% β-ca3(po4)2/mg–6% zn composites exhibit good corrosion resistance, as determined by a 30 day immersion test and electrochemical measurements in sbf at 37 °c. the 10% β-ca3(po4)2/mg–6% zn composite is safe for cellular applications, with a cytotoxicity grade of ∼0–1 against l929 cells in in vitro testing. the β-ca3(po4)2/mg–6% zn composite also exhibits good biocompatibility with the tissue and the important visceral organs the heart, kidney and liver of experimental rabbits. the composite has a suitable degradation rate and improves the concrescence of a pre-broken bone. the corrosion products, such as mg(oh)2 and ca5(po4)6(oh)2, can improve the biocompatibility of the β-ca3(po4)2/mg–zn composite.

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