اینستاگرام تی پی بین
همایش ، رویداد ، ژورنال
حوزه های تحت پوشش رویداد
  • preparation, structure and anticoagulant activity of a low molecular weight fraction produced by mild acid hydrolysis of sulfated rhamnan from monostroma latissimum

    جزئیات بیشتر مقاله
    • تاریخ ارائه: 1390/01/01
    • تاریخ انتشار در تی پی بین: 1390/01/01
    • تعداد بازدید: 614
    • تعداد پرسش و پاسخ ها: 0
    • شماره تماس دبیرخانه رویداد: -
     a low molecular weight fraction, designated lmwp, was prepared by mild acid hydrolysis of sulfated rhamnan from monostroma latissimum and purified by anion-exchange and gel-permeation chromatography. chemical and spectroscopic analyses showed that lmwp was mainly composed of rhamnose, and its molecular weight was about 33.6 kda. the backbone of lmwp consists of 1,3-linked α-l-rhamnose units with partially sulfate groups at the c-2 position. approximately 25% of 1,3-linked α-l-rhamnose units is substituted at c-2 by sulfated or non-sulfated 1,3-linked α-l-rhamnose and 1,2-linked α-l-rhamnose units. lmwp effectively prolonged clotting time as evaluated by the activated partial thromboplastin time assay and was a potent thrombin inhibitor mediated by heparin cofactor ii. the investigation demonstrated that lmwp is a novel sulfated polysaccharide with anticoagulant activity.

سوال خود را در مورد این مقاله مطرح نمایید :

با انتخاب دکمه ثبت پرسش، موافقت خود را با قوانین انتشار محتوا در وبسایت تی پی بین اعلام می کنم
مقالات جدیدترین رویدادها
مقالات جدیدترین ژورنال ها