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  • a mathematical model of hepatitis e virus transmission and its application for vaccination strategy in a displaced persons camp in uganda

    جزئیات بیشتر مقاله
    • تاریخ ارائه: 1394/01/01
    • تاریخ انتشار در تی پی بین: 1394/01/01
    • تعداد بازدید: 417
    • تعداد پرسش و پاسخ ها: 0
    • شماره تماس دبیرخانه رویداد: -
     hepatitis e virus is an enterically transmitted disease that mainly effects people in developing countries. the dynamics and the factors causing outbreaks of these diseases can be better understood using mathematical models, which are fit to data. here we investigate the dynamics of a hepatitis e outbreak in internally displaced persons (idp) camps in sudan and uganda during 2007 to 2009. we use the data to determine that r0 is approximately 2.25 for the outbreak. secondly, we use a model to estimate that the critical level of latrine and bore hole coverages needed to eradicate the epidemic is at least 16% and 17% respectively. lastly, we further investigate the relationship between the co-infection factor for malaria and hepatitis e on the value of r0 for hepatitis e. taken together, these results provide us with a better understanding of the dynamics and possible causes of hepatitis e outbreaks.

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