• reduced tissue hardness of trabecular bone is associated with severe osteoarthritis

    جزئیات بیشتر مقاله
    • تاریخ ارائه: 1390/06/01
    • تاریخ انتشار در تی پی بین: 1390/06/01
    • تعداد بازدید: 328
    • تعداد پرسش و پاسخ ها: 0
    • شماره تماس دبیرخانه رویداد: -

    this study investigated whether changes in hardness of human trabecular bone are associated with osteoarthritis. twenty femoral heads extracted from subjects without musculoskeletal diseases (subject age: 49–83 years) and twenty femoral heads extracted from osteoarthritic subjects (subject age: 42–85 years) were tested. sixty indentations were performed along the main trabecular direction of each sample at a fixed relative distance. two microstructures were found on the indenting locations: packs of parallel-lamellae (pl) and secondary osteons (so). a 25 gf load was applied for 15 s and the vickers hardness (hv) was assessed. trabecular tissue extracted from osteoarthritic subjects was found to be about 13% less hard compared to tissue extracted from non-pathologic subjects. however, tissue hardness was not significantly affected by gender or age. the so was 10% less hard than the pl for both pathologic and non-pathologic tissues. a hardness of 34.1 hv for pl and 30.8 hv for so was found for the non-pathologic tissue. for osteoarthritic tissue, the hardness was 30.2 hv for pl and 27.1 hv for so. in the bone tissue extracted from osteoarthritic subjects the occurrence of indenting a so (28%) was higher than that observed in the non-pathological tissue (15%). osteoarthritis is associated with reduced tissue hardness and alterations in microstructure of the trabecular bone tissue. gender does not significantly affect trabecular bone hardness either in non-pathological or osteoarthritic subjects. a similar conclusion can be drawn for age, although a larger donor sample size would be necessary to definitively exclude the existence of a slight effect.

سوال خود را در مورد این مقاله مطرح نمایید :

با انتخاب دکمه ثبت پرسش، موافقت خود را با قوانین انتشار محتوا در وبسایت تی پی بین اعلام می کنم
مقالات جدیدترین رویدادها
مقالات جدیدترین ژورنال ها