• using static preload with magnetic resonance elastography to estimate large strain viscoelastic properties of bovine liver

    جزئیات بیشتر مقاله
    • تاریخ ارائه: 1390/06/01
    • تاریخ انتشار در تی پی بین: 1390/06/01
    • تعداد بازدید: 360
    • تعداد پرسش و پاسخ ها: 0
    • شماره تماس دبیرخانه رویداد: -

    traditional magnetic resonance elastography (mre) applies small amplitude vibration to tissues. thus currently mre measures only the small deformation behaviour of tissues. mre has the potential to estimate the strain-varying shear modulus of soft tissues, if applied at different static strains, which may allow prediction of the large-strain behaviour of tissues. this study uses mre of bovine liver specimens under various levels of static compressive pre-strain up to 30%. storage and loss moduli measured using mre increased non-linearly with static compressive pre-strain, and exponential models fit well to these data to describe this relationship (r2>0.93). based on these models, a 10% linear compression of liver would result in a 47% overestimate of the ‘true’ storage modulus of the uncompressed tissue. the results of this study have implications for mre transducer design and interpretation of results from in vivo mre studies.

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