• antipseudomonal activity of artemisia quettensis essential oil and its synergy with imipenem

    جزئیات بیشتر مقاله
    • تاریخ ارائه: 1397/12/20
    • تاریخ انتشار در تی پی بین: 1397/12/20
    • تعداد بازدید: 352
    • تعداد پرسش و پاسخ ها: 0
    • شماره تماس دبیرخانه رویداد: -

    subject: pseudomonas aeruginosa is recognized as one of the major cause of infections in communities and hospitals. in this study,the chemical composition and antipseudomonal alactivity of artemisia quettensis essential oil were evaluated, along with its synergistic activity with imipenem.

    research method: the essential oil was obtained by hydrodistillation from aerial parts of the plant and analyzed using gc and gc-ms. antibacterial activity of the oil was evaluated by agar dilution assay against clinical isolates of pseudomonas aeruginosa. the essential oil exhibited synergism with imipenem and displayed the ability to enhance the activity of imipenem.

    summary: the main chemical composition of a.quettensis oil included homoadamantane, camphor, eugenol. the oil and antibiotic showed high antibacterial activity against pseudomonas aeruginosa with minimal inhibitory concentration (mic) 0.5 μl/ml and 16 μg/ml, respectively. the synergistic action was evaluated. the essential oil exhibited synergism with imipenem and displayed the ability to enhance the activity of imipenem. the main purpose of this research is synergism effect, the oil and antibiotic showed mic 0.2 μl/ml and antibiotics 4 μg/ml, respectively.

    aims: artemisia quettensis tested showed good bactericidal effect because of the synergistic search by injecting a quarter of antibiotics inhibit the growth of bacteria and prevents the creation of the colony. the essential oils have antibacterial power of antibiotics to 4 fold increase.

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