application of nio nanoparticle as an effective catalyst for aldol reaction of aryl alkyl ketones with aromatic and heteroaromatic aldehydes

nickel oxide (nio) nanoparticles (nps) were used as catalyst in aldol reactions of aryl alkyl ketones with aromatic and heteroaromatic aldehydes. nio nps were used in low concentration for efficient cross aldol reactions in moderate to good yields. this reported method illustrates several advantages such as environmental friendly reaction conditions, simplicity, short reaction time, easy work up, low ketone to aldehyde ratio, and recyclability of the catalyst.