This study evaluated the effectiveness and performance of smoke management models in a TFT-LCD cleanroom. Several smoke management models are discussed in a distinct 3-level cleanroom compartment. The tools used included a fire dynamics simulator (FDS) and SIMULEX. The design fires were 3 MW and 5.4 MW in ultra fast fire, respectively. In life safety, both a downward smoke exhaust system and upward smoke exhaust system, incorporating a decrease of filter fan unit air supply rate, could be ...