مقاله Comparative study on the interactions of cationic gemini and single-chain surfactant micelles with curcumin : تی پی بین

خلاصه مقاله

The interactions of curcumin with cationic micelles of gemini surfactant trimethylene-1,3-bis-(dodecyldimethyl ammonium bromide) (C₁₂C₃C₁₂Br₂) and single-chain surfactant dodecyltrimethylammonium bromide (DTAB) were investigated. At pH 13, the trianionic curcumin (Cur³⁻) had rapid degradation to about 21.5% with an observed rate constant (k_obs) of 0.0402 h⁻¹ in water, whereas DTAB micelle and C₁₂C₃C₁₂Br₂ micelle can suppress Cur³⁻ degradation to 9.6% with k_obs = 0.0174 h⁻¹ and to 5.0% with k_obs = 0.00782 h⁻¹, respectively. Cur³⁻ also showed higher intensities of characteristic peaks with the position changes in absorption and fluorescence spectra as well as increased anisotropy (r) in two surfactant micelles than in water. These results were ascribed to the solubilization of Cur³⁻ in the palisade layer of DTAB and C₁₂C₃C₁₂Br₂ micelles through the attractive electrostatic interactions between negatively charged groups of Cur³⁻ and quaternary ammonium headgroups of surfactants, which was also supported by the values of lowest pK_a (pK_a1) and corresponding thermodynamic parameters of curcumin in water, DTAB and C₁₂C₃C₁₂Br₂ micelles. The stronger electrostatic attractions between Cur³⁻ and the micelle of C₁₂C₃C₁₂Br₂ brought about more increased stability of Cur³⁻ and more remarkable changes in absorption and fluorescence spectra of Cur³⁻ in C₁₂C₃C₁₂Br₂ micelle than in DTAB micelle.

نویسندگان

Zizhen Wan [ School of Chemistry and Molecular Engineering, East China University of Science and Technology, Shanghai 200237, China ]

Dan Ke [ School of Chemistry and Molecular Engineering, East China University of Science and Technology, Shanghai 200237, China ]

Jinxiang Hong [ State Key Laboratory of High Performance Civil Engineering Materials, Jiangsu Academy of Building Science Co., Ltd., Nanjing 210008, China ]

Qianping Ran [ State Key Laboratory of High Performance Civil Engineering Materials, Jiangsu Academy of Building Science Co., Ltd., Nanjing 210008, China ]

Weiguo Shen [ School of Chemistry and Molecular Engineering, East China University of Science and Technology, Shanghai 200237, China ]

کلمات کلیدی

Micelle Curcumin Stability Absorption Fluorescence

آدرس این مقاله

آدرس مستقیم دسترسی به این مقاله

مشخصات کنفرانس

مشاهده مقالات

Colloids and Surfaces A: Physicochemical and Engineering Aspects

Colloids and Surfaces A: Physicochemical and Engineering Aspects is an international journal devoted to the science underlying applications ofcolloids and interfacial phenomena. The journal aims at publishing high quality research papers featuring new materials or new insights into the role of colloid and interface science in (for example) food, energy, minerals processing, pharmaceuticals or the environment.Criteria for publication in Colloids and Surfaces A are novelty, quality and current interest. Manuscripts which only make routine use of or minor extensions to well established methodologies (e.g. fitting adsorption data to a Langmuir or Freundlich isotherm) are no appropriate for the journal.

حوزه های تحت پوشش : Physicochemical , food, energy, minerals processing, pharmaceuticals , environment