محبوبترین نویسندگان :
نویسندگان مقالات پربازدید :
آکتا بیومتریال
جزئیات رویداد
همایش ، رویداد ، ژورنال
اینستاگرام تی پی بین
حوزه های تحت پوشش رویداد

  • healing of complement activating ti implants compared with non-activating ti in rat tibia

    نویسندگان :
    کلمات کلیدی :
    جزئیات بیشتر مقاله
    • تاریخ ارائه: 1392/01/01
    • تاریخ انتشار در تی پی بین: 1392/01/01
    • تعداد بازدید: 717
    • تعداد پرسش و پاسخ ها: 0
    • شماره تماس دبیرخانه رویداد: -
     recent studies have revealed that ozone ultraviolet (uvo) illumination of titanium (ti) implants improves bone–implant anchorage by altering the physico-chemical and immune activating properties of the titanium dioxide (tio2) layer. in the present rat tibia model, the authors compared the early events of inflammation and bone formation around uvo-treated ti and complement activating immunoglobin g (igg)-coated ti. machined ti and machined ti coated with a physical vapour-deposited ti layer were used as references. screw-shaped test and reference implants were implanted into rat tibia and harvested after 1, 7 and 28 days. messenger rna expression of implant adhered cells and peri-implant tissue ∼250 μm from the surface were subsequently analysed with regard to il-1β, tnf-α, osteocalcin, cathepsin k, bmp-2 and pdgf. separate implants were retrieved after 7 and 28 days for removal torque measurements, and histological staining and histomorphometric analysis of bone area and bone-to-implant contact. while enhanced expression of inflammatory markers, tnf-α and il-1β, was observed on igg-coated surfaces throughout the observation time, uvo-treated surfaces indicated a significantly lower early inflammatory response. in the early phases (1 and 7 days), the uvo-treated surfaces displayed a significantly higher expression of osteoblast markers bmp-2 and osteocalcin. in summary, complement activating ti implants elicited a stronger inflammatory response than uvo-treated ti, with low complement activation during the first week of healing. in spite of this, the uvo-treated ti induced only marginally more bone growth outside the implants.

سوال خود را در مورد این مقاله مطرح نمایید :

با انتخاب دکمه ثبت پرسش، موافقت خود را با قوانین انتشار محتوا در وبسایت تی پی بین اعلام می کنم
مقالات جدیدترین رویدادها
مقالات جدیدترین ژورنال ها