one-pot three-component synthesis of 2,3-dihydroquinazolin-4(1h)-ones by fe3o4@sio2/schiff base complex of cu(ii)

fe₃o₄@sio₂/schiff base complex of cu(ii) efficiently catalyzes condensation reaction of isatoic anhydride, aldehydes, and primary amines or ammonium salts to afford the corresponding 2,3-dihydroquinazolin-4(1h)-one derivatives in ethanol under reflux conditions. this method gives notable advantages such as easy work-up, high yields, short reaction times. also, the aforementioned nanocatalyst can be easily recovered by a magnetic field and reused for subsequent reactions for at least 8 times without noticeable deterioration in catalytic activity.