phytochemical, heavy metals and antimicrobial study of the leaves of calopogonium mucunoides

phytochemical, heavy metals and antimicrobial study of the leaves of calopogonium mucunoides

in this study, the phytochemical, heavy metal, and antimicrobial characteristics of the leaves of calopogonium mucunoides, a popular plant in nigeria’s folk medicine, were investigated in order to determine its therapeutic potential. the phytochemicals present in the leaves were extracted with n-hexane, methanol, and ethyl acetate, and the extracts were used to investigate the phytochemical constituents and antimicrobial activity. he content of five heavy metals was determined using the methanol extract.

several secondary metabolites were found in varied amounts, according to the results. lead (0.08 mg/kg) and iron (0.08 mg/kg) were found to be well below the world health organization's permissible limits for heavy metals in plants, while cadmium, nickel, and zinc were found to be below detectable levels. using the disk diffusion method, the extracts were evaluated against thirteen human pathogens (ten bacteria and three fungi). the extracts were shown to have a wide variety of antibacterial properties, with the methanolic extract having the largest zone of inhibition (31 mm) against bacillus sp., while the n-hexane extract had no antimicrobial action in the entire test species. the results obtained revealed that the leaves of c. mucunoides have some therapeutic values and could be exploited in the preparation of herbal drugs for the treatment of various ailments