• synthesis and antibacterial activities of novel 1-bromo-2-(6-bromo-1,2,3,4-tetrahydro-9h-carbazol-1-yl) ethanone and 1-bromo-2-(5-bromo-1,2,3-trihydrocyclopenta[b]indole-1-yl) ethanone

    جزئیات بیشتر مقاله
    • تاریخ ارائه: 1400/11/11
    • تاریخ انتشار در تی پی بین: 1400/11/11
    • تعداد بازدید: 96
    • تعداد پرسش و پاسخ ها: 0
    • شماره تماس ژورنال: 09122976055

    synthesis and antibacterial activities of novel 1-bromo-2-(6-bromo-1,2,3,4-tetrahydro-9h-carbazol-1-yl) ethanone and 1-bromo-2-(5-bromo-1,2,3-trihydrocyclopenta[b]indole-1-yl) ethanone

     nitrogen containing hetero cyclic compounds constitute the interior structure of a number of biologically attracted compounds against bacteria and fungi. the synthesis of carbazole derivatives have been desire due to their importance in medicinal field. enhanced approach of fischer’s synthesis followed by bromoacetylation have been used to synthesis four different carbazole derivatives, namely 1-bromo-2-(6-bromo-1,2,3,4-tetrahydro-9h-carbazol-1-yl) ethanone,1-bromo-2-(5-bromo-1,2,3-trihydrocyclopenta[b]indole-1-yl) ethanone. the synthesized compounds were identified and confirmed using spectral techniques viz, ftir, 1h nmr, 13c nmr, mass spectroscopy. antibacterial evaluation of synthesized compounds found to have pronozed antibacterial activity.

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